ABHD17B

Across TCGA cell cohorts, ABHD17B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ABHD17B-associated genes across cancer lineages are FCN2, PRKACG, and INSL5. Each is linked with ABHD17B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17B-to-partner and partner-to-ABHD17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCN2 grouped by ABHD17B-low versus ABHD17B-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17B→partner) and Y-score (partner→ABHD17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FCN2 →	+0.033	+5.087	<.001	.004	3	1
URINARY_TRACT	PRKACG →	+0.006	+5.087	<.001	.004	3	1
LARGE_INTESTINE	INSL5 →	+0.401	+3.626	<.001	.006	3	1
CNS	OR1E2 →	+0.455	+5.321	<.001	.005	3	1
CNS	OR1E1 →	+0.504	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FCN2 by ABHD17B expression — URINARY_TRACT

Explore this box plot interactively →