Across TCGA pan-cancer cohorts, ABHD17AP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ABHD17AP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ABHD17AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABHD17AP1 is over-expressed in tumor.
KIRC, COAD, and LIHC are the cancer types where ABHD17AP1 tumor–normal differential expression is most reproducible.