ABHD16A

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD16A mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD16A-associated genes across cancer lineages are A-Raf_pS299, Ku80, and p21. Each is linked with ABHD16A in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD16A-to-partner and partner-to-ABHD16A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD16A→partner) and Y-score (partner→ABHD16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECA-Raf_pS299 →-0.153-2.459.006.01931
UCECKu80 →+0.280+1.887.010.03131
UCECp21 →+0.248+2.820.005.03531
UCECp27_pT157 →-0.071-3.282.008.01031
UCECRab25 →-0.326-2.584.034.01131
UCECSTAT5a →+0.400+3.000.032.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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