ABHD11

Across TCGA pan-cancer cohorts, ABHD11 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABHD11 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ABHD11 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ABHD11 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where ABHD11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.898	0.665	.009	24	view →
PDAC	OS	Median	III,IV	0.195	0.612	.007	19	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	7	view →
CCRCC	DFS	Tertile	II,III,IV	0.588	0.848	.042	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABHD11–LSCC (DFS)

Open the LSCC breakdown →