ABCG2

Across TCGA patient cohorts, ABCG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,505 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ABCG2-associated proteins across cancer lineages are PRKG1, MYO1C, and KANK2_S540. Each is linked with ABCG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCG2-to-partner and partner-to-ABCG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCG2 versus PRKG1 in UCEC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCG2→partner) and Y-score (partner→ABCG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.697	+1.081	<.001	<.001	3	7
BRCA	MYO1C →	+0.542	+0.831	<.001	<.001	3	7
LSCC	KANK2_S540 →	+0.641	+0.614	.001	.003	3	7
BRCA	LAMB2 →	+0.709	+0.758	<.001	<.001	3	7
UCEC	SVIL_S547 →	+1.627	+1.327	<.001	<.001	3	7
GBM	SPTAN1 →	+0.321	+0.617	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,505 associations by consensus.

ABCG2 vs PRKG1 — UCEC

Explore this scatter interactively →