ABCF3

Across TCGA pan-cancer cohorts, ABCF3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABCF3 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ABCF3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCF3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where ABCF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	0.345	0.782	.015	21	view →
PDAC	OS	Tertile	All	0.394	0.620	.010	21	view →
HNSC	DFS	Median	II,III,IV	0.981	0.888	.004	14	view →
LUAD	DFS	Quartile	All	0.567	1.000	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABCF3–CCRCC (DFS)

Open the CCRCC breakdown →