ABCF3

Across TCGA patient cohorts, ABCF3 mutation is significantly associated with the RNA expression of many other genes, with 3,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCF3-associated genes across cancer lineages are IQCC, ZFYVE19, and GLMN. Each is linked with ABCF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCF3-to-partner and partner-to-ABCF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCC grouped by ABCF3-low versus ABCF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCF3→partner) and Y-score (partner→ABCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IQCC →	+0.409	+1.736	.005	.007	3	3
SKCM	ZFYVE19 →	+0.498	+3.745	<.001	<.001	3	3
UCEC	GLMN →	+0.484	+3.595	.002	.001	3	3
UCEC	TIPIN →	+0.642	+3.606	<.001	<.001	3	3
UCEC	LIN52 →	+0.466	+3.849	<.001	<.001	3	3
CESC	LINC02559 →	+1.058	+4.757	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,914 associations by consensus.

IQCC by ABCF3 expression — UCEC

Explore this box plot interactively →