ABCF3

Across TCGA patient cohorts, ABCF3 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCF3-associated genes across cancer lineages are ASNS, ATM, and c-Met_pY1235. Each is linked with ABCF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCF3-to-partner and partner-to-ABCF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ABCF3-low versus ABCF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCF3→partner) and Y-score (partner→ABCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.502	+2.330	.004	.020	3	2
COAD	ATM →	-0.560	-3.000	.001	.034	3	2
COAD	c-Met_pY1235 →	+0.131	+2.364	.003	.018	3	2
COAD	4E-BP1 →	+0.316	+3.000	.001	.035	3	2
UCEC	PCNA →	+0.213	+1.874	.008	.049	3	2
UCEC	Rad50 →	-0.213	-3.156	.019	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by ABCF3 expression — COAD

Explore this box plot interactively →