ABCF3

Across TCGA cell cohorts, ABCF3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCF3-associated genes across cancer lineages are GFRA2, DPP10, and CD300A. Each is linked with ABCF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCF3-to-partner and partner-to-ABCF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA2 grouped by ABCF3-low versus ABCF3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCF3→partner) and Y-score (partner→ABCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GFRA2 →	+0.037	+2.928	<.001	.003	3	1
LARGE_INTESTINE	DPP10 →	+0.917	+3.662	<.001	.002	3	1
LARGE_INTESTINE	CD300A →	+0.165	+3.201	.001	.009	2	1
LARGE_INTESTINE	SFTPB →	+0.164	+3.285	.002	.007	2	1
LARGE_INTESTINE	ACER1 →	+0.100	+2.560	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GFRA2 by ABCF3 expression — LARGE_INTESTINE

Explore this box plot interactively →