ABCF2

Across TCGA pan-cancer cohorts, ABCF2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABCF2 data layer compared with 26 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ABCF2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCF2 expression acts as an unfavorable survival marker.

OV, ESCA, and UCEC are the cancer types where ABCF2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.242	0.542	.002	24	view →
ESCA	OS	Median	All	0.022	0.701	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABCF2–OV (DFS)

Open the OV breakdown →