ABCF2

Across TCGA cell cohorts, ABCF2 mutation is significantly associated with the RNA expression of many other genes, with 389 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCF2-associated genes across cancer lineages are NKX2-6, TLE7, and OR5AK2. Each is linked with ABCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCF2-to-partner and partner-to-ABCF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKX2-6 grouped by ABCF2-low versus ABCF2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCF2→partner) and Y-score (partner→ABCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
BLOOD_Lymphoma	OR5AK2 →	+0.031	+4.247	<.001	.004	3	1
BLOOD_Lymphoma	OR2L8 →	+0.021	+3.584	<.001	.004	3	1
OVARY	NLRP8 →	+0.006	+5.196	<.001	.005	3	1
OVARY	SUPT20HL1 →	+0.123	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 389 associations by consensus.

NKX2-6 by ABCF2 expression — BLOOD_Leukemia

Explore this box plot interactively →