Across TCGA cell cohorts, ABCF1 mutation is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCF1-associated genes across cancer lineages are AVP, OR5C1, and LCN9. Each is linked with ABCF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCF1-to-partner and partner-to-ABCF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCF1→partner) and Y-score (partner→ABCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.038	+5.209	<.001	.005	3	2
SOFT_TISSUE	OR5C1 →	+0.027	+3.635	<.001	.007	3	1
SOFT_TISSUE	LCN9 →	+0.060	+3.635	.003	.007	3	1
SOFT_TISSUE	BTNL2 →	+0.203	+4.459	.003	.001	3	1
SOFT_TISSUE	OR13C2 →	+0.018	+4.392	<.001	.004	3	1
BLOOD_Leukemia	MYL7 →	+0.057	+4.339	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

Exploration

ABCF1 survival (RNA) · tumor vs normal (RNA) · all ABCF1 data types