ABCE1

Across TCGA pan-cancer cohorts, ABCE1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ABCE1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ABCE1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ABCE1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where ABCE1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	III,IV	0.202	0.985	.007	31	view →
GBM	DFS	Tertile	All	0.578	0.819	<.001	19	view →
HNSC	OS	Tertile	All	1.000	0.924	.013	15	view →
PDAC	DFS	Tertile	II,III,IV	0.230	0.509	.005	13	view →
UCEC	DFS	Tertile	III,IV	1.000	0.457	.042	8	view →
LUAD	OS	Median	II,III,IV	0.336	1.000	<.001	8	view →
LSCC	DFS	Quartile	III,IV	0.365	0.826	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ABCE1–CCRCC (OS)

Open the CCRCC breakdown →