ABCD2

Across TCGA patient cohorts, ABCD2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,540 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCD2-associated genes across cancer lineages are TRIOBP, MLC1, and CDKL1. Each is linked with ABCD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCD2-to-partner and partner-to-ABCD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCD2 versus TRIOBP in GBM, with a Pearson correlation of 0.21.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCD2→partner) and Y-score (partner→ABCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIOBP →	+0.241	+0.350	.007	.005	3	1
GBM	MLC1 →	+1.052	+0.516	.001	.001	3	1
GBM	CDKL1 →	-0.410	-0.406	<.001	.001	3	1
GBM	SLC8A3 →	-1.241	-0.463	<.001	.002	3	1
GBM	ZFYVE21 →	+0.589	+0.536	<.001	<.001	3	1
GBM	CPNE6 →	+0.699	+0.284	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,540 associations by consensus.

ABCD2 vs TRIOBP — GBM

Explore this scatter interactively →