ABCD2

Across TCGA cell cohorts, ABCD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,058 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ABCD2-associated GO terms across cancer lineages are Membrane fusion, Negative regulation of vascular associated smooth muscle contraction, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with ABCD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCD2-to-partner and partner-to-ABCD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane fusion grouped by ABCD2-low versus ABCD2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCD2→partner) and Y-score (partner→ABCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Membrane fusion →	+0.027	+0.981	.002	.005	3	5
BLOOD_Lymphoma	Negative regulation of vascular associated smooth muscle contraction →	-0.132	-1.007	.001	<.001	3	5
BLOOD_Lymphoma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.046	+1.011	<.001	<.001	3	5
OESOPHAGUS	Regulation of neutrophil degranulation →	-1.532	-0.036	<.001	.006	3	4
BLOOD_Lymphoma	Positive regulation of viral entry into host cell →	+0.099	+1.117	<.001	.001	3	4
BLOOD_Lymphoma	Positive regulation by symbiont of entry into host →	+0.099	+1.117	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,058 associations by consensus.

Membrane fusion by ABCD2 expression — BLOOD_Lymphoma

Explore this box plot interactively →