Across TCGA pan-cancer cohorts, ABCD1P5 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ABCD1P5’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ABCD1P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABCD1P5 is over-expressed in tumor.
LUSC are the cancer types where ABCD1P5 tumor–normal differential expression is most reproducible.