ABCC9

Across TCGA patient cohorts, ABCC9 mutation is significantly associated with the RNA expression of many other genes, with 5,876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCC9-associated genes across cancer lineages are CDCA5, PSMB5, and CKAP2L. Each is linked with ABCC9 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCC9-to-partner and partner-to-ABCC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA5 grouped by ABCC9-low versus ABCC9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC9→partner) and Y-score (partner→ABCC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA5 →	+0.638	+1.673	<.001	<.001	3	6
LUAD	PSMB5 →	+0.447	+3.611	.001	.001	3	6
COAD	CKAP2L →	+0.705	+2.598	<.001	.006	3	6
BLCA	CDKN3 →	+0.953	+3.584	<.001	.002	3	5
UCEC	PARP2 →	+0.424	+1.662	<.001	<.001	3	5
BLCA	DAD1 →	+0.473	+2.814	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,876 associations by consensus.

CDCA5 by ABCC9 expression — UCEC

Explore this box plot interactively →