ABCC9

Across TCGA cell cohorts, ABCC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,142 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ABCC9-associated GO terms across cancer lineages are Negative regulation of protein catabolic process, Protein activation cascade, and Positive regulation of actin filament bundle assembly. Each is linked with ABCC9 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCC9-to-partner and partner-to-ABCC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein catabolic process grouped by ABCC9-low versus ABCC9-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC9→partner) and Y-score (partner→ABCC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of protein catabolic process →	+0.047	+1.094	.001	.003	3	7
BONE	Protein activation cascade →	+0.316	+1.660	<.001	.005	3	7
LARGE_INTESTINE	Positive regulation of actin filament bundle assembly →	+0.037	+0.729	.008	.002	3	6
LARGE_INTESTINE	Ionotropic glutamate receptor signaling pathway →	-0.124	-0.858	.001	.009	3	6
SOFT_TISSUE	Biological process involved in interaction with symbiont →	+0.217	+1.274	<.001	<.001	3	6
SOFT_TISSUE	Process utilizing autophagic mechanism →	+0.039	+0.792	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,142 associations by consensus.

Negative regulation of protein catabolic process by ABCC9 expression — SOFT_TISSUE

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