ABCC6P1

Across TCGA pan-cancer cohorts, ABCC6P1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ABCC6P1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ABCC6P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABCC6P1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

THCA, KICH, and LUSC are the cancer types where ABCC6P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABCC6P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	III,IV	+1.356	<.001	11	view →
KICH	Female	II,III,IV	−1.758	<.001	9	view →
LUSC	Female	All	−1.210	<.001	9	view →
KIRC	Male	II,III,IV	+1.067	<.001	8	view →
BRCA	All	All	−0.390	<.001	6	view →
COAD	Female	All	−0.602	.003	4	view →
LUAD	Male	All	−0.470	.001	4	view →
CHOL	All	All	−1.765	<.001	2	view →
PRAD	All	All	−0.264	<.001	2	view →
LIHC	Female	III,IV	+0.881	.030	1	view →
STAD	All	IV	−0.679	.042	1	view →
BLCA	All	IV	−0.067	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ABCC6P1–THCA

Open the THCA breakdown →