ABCC6

Across TCGA patient cohorts, ABCC6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,929 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ABCC6-associated genes across cancer lineages are SDC4, SNX30, and HSPB8. Each is linked with ABCC6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC6-to-partner and partner-to-ABCC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC6 versus SDC4 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC6→partner) and Y-score (partner→ABCC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDC4 →	+0.851	+0.582	<.001	.001	3	3
LUAD	SNX30 →	+0.838	+0.517	<.001	<.001	3	3
LSCC	HSPB8 →	+1.076	+0.602	.005	.006	3	3
LUAD	GJB1 →	+1.554	+0.626	.001	<.001	3	3
LSCC	SPTLC3 →	+1.265	+0.831	<.001	<.001	3	3
LUAD	CYP4A11 →	+1.635	+0.586	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,929 associations by consensus.

ABCC6 vs SDC4 — LSCC

Explore this scatter interactively →