ABCC6

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ABCC6 RNA expression is significantly associated with the RNA expression of many other genes, with 8,436 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCC6-associated genes across cancer lineages are METTL7B, TMEM37, and ALDH2. Each is linked with ABCC6 in more than 8 cancer types. Because this analysis shows association rather than direction, both ABCC6-to-partner and partner-to-ABCC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC6 versus METTL7B in PANCREAS, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC6→partner) and Y-score (partner→ABCC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASMETTL7B →+2.359+1.241<.001<.00139
LIVERTMEM37 →+2.607+2.852.007.00138
LUNG_NSCLC_LUADALDH2 →+3.010+1.363<.001<.00137
URINARY_TRACTFCGRT →+2.977+1.166<.001.00137
LIVERMLXIPL →+2.855+2.439<.001<.00137
LUNG_NSCLC_LUSCQPRT →+3.825+1.782<.001.00127
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,436 associations by consensus.

ABCC6 vs METTL7B — PANCREAS

Per-sample scatter of ABCC6 vs METTL7B in PANCREAS (Pearson r = 0.77).

Explore this scatter interactively →

Exploration