ABCC6

Across TCGA cell cohorts, ABCC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,741 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCC6-associated GO terms across cancer lineages are Response to sodium phosphate, Fatty acid catabolic process, and Fatty acid beta-oxidation. Each is linked with ABCC6 in more than 16 cancer types. Because this analysis shows association rather than direction, both ABCC6-to-partner and partner-to-ABCC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to sodium phosphate grouped by ABCC6-low versus ABCC6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC6→partner) and Y-score (partner→ABCC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to sodium phosphate →	-0.311	-1.467	<.001	<.001	3	17
LIVER	Fatty acid catabolic process →	+0.102	+2.923	.003	<.001	3	11
LIVER	Fatty acid beta-oxidation →	+0.123	+3.555	<.001	<.001	3	10
LIVER	Organic acid catabolic process →	+0.088	+3.253	<.001	<.001	3	9
LIVER	Nonribosomal peptide biosynthetic process →	+0.287	+3.321	.001	<.001	3	9
LIVER	Fatty acid oxidation →	+0.093	+3.171	.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,741 associations by consensus.

Response to sodium phosphate by ABCC6 expression — STOMACH

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