ABCC5

Across TCGA patient cohorts, ABCC5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,960 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCC5-associated genes across cancer lineages are ASF1B, MAPK10, and SLC6A8. Each is linked with ABCC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC5-to-partner and partner-to-ABCC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC5 versus ASF1B in LSCC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC5→partner) and Y-score (partner→ABCC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ASF1B →	+0.793	+0.696	<.001	.001	3	3
HNSC	MAPK10 →	+0.843	+0.663	<.001	<.001	3	3
LSCC	SLC6A8 →	+1.201	+0.754	<.001	<.001	3	3
LSCC	NTS →	+3.822	+1.136	<.001	<.001	3	3
GBM	NPL →	+1.133	+0.646	.007	.006	3	3
GBM	GPNMB →	+1.400	+0.424	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,960 associations by consensus.

ABCC5 vs ASF1B — LSCC

Explore this scatter interactively →