ABCC5

Across TCGA cell cohorts, ABCC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,660 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCC5-associated GO terms across cancer lineages are Glutathione transport, Positive regulation of DNA repair, and Nucleic acid catabolic process. Each is linked with ABCC5 in more than 15 cancer types. Because this analysis shows association rather than direction, both ABCC5-to-partner and partner-to-ABCC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutathione transport grouped by ABCC5-low versus ABCC5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC5→partner) and Y-score (partner→ABCC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Glutathione transport →	+0.182	+1.833	<.001	<.001	3	16
BONE	Positive regulation of DNA repair →	+0.065	+0.739	.002	.005	3	16
BONE	Nucleic acid catabolic process →	+0.065	+0.860	<.001	.002	3	15
LUNG_NSCLC_LUSC	Hyaluronan biosynthetic process →	+1.066	+1.850	.001	<.001	3	15
BONE	Establishment of RNA localization →	+0.132	+1.019	<.001	.001	3	15
BONE	RNA catabolic process →	+0.084	+1.171	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,660 associations by consensus.

Glutathione transport by ABCC5 expression — OESOPHAGUS

Explore this box plot interactively →