ABCC4

Across TCGA patient cohorts, ABCC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,239 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABCC4-associated proteins across cancer lineages are ABCC4_T646, ABCC4_S404, and EPB41L2. Each is linked with ABCC4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ABCC4-to-partner and partner-to-ABCC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC4 versus ABCC4_T646 in LUAD, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC4→partner) and Y-score (partner→ABCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ABCC4_T646 →	+1.007	+1.334	<.001	<.001	3	8
LUAD	ABCC4_S404 →	+1.107	+1.400	<.001	<.001	3	8
GBM	EPB41L2 →	+0.464	+0.569	<.001	<.001	3	4
HNSC	MAP7D1_S460 →	-0.580	-0.511	<.001	<.001	3	4
LSCC	SPAST →	+0.380	+0.526	<.001	<.001	3	4
LUAD	ABCC4_S655 →	+1.476	+1.274	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,239 associations by consensus.

ABCC4 vs ABCC4_T646 — LUAD

Explore this scatter interactively →