ABCC4

Across TCGA patient cohorts, ABCC4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,446 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ABCC4-associated genes across cancer lineages are ZWINT, CH25H, and HAUS1. Each is linked with ABCC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC4-to-partner and partner-to-ABCC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC4 versus ZWINT in GBM, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC4→partner) and Y-score (partner→ABCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZWINT →	-0.967	-0.353	<.001	.001	3	3
GBM	CH25H →	+1.598	+0.350	<.001	<.001	3	3
GBM	HAUS1 →	-0.548	-0.384	<.001	<.001	3	3
GBM	FBXO43 →	-0.519	-0.258	.002	.003	3	3
BRCA	RCAN1 →	+0.623	+0.530	.006	.001	3	3
UCEC	POLR3K →	-0.559	-0.466	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,446 associations by consensus.

ABCC4 vs ZWINT — GBM

Explore this scatter interactively →