ABCC4

Across TCGA cell cohorts, ABCC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,284 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCC4-associated GO terms across cancer lineages are Prostaglandin secretion, Oligopeptide transport, and Guanine nucleotide transport. Each is linked with ABCC4 in more than 19 cancer types. Because this analysis shows association rather than direction, both ABCC4-to-partner and partner-to-ABCC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Prostaglandin secretion grouped by ABCC4-low versus ABCC4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC4→partner) and Y-score (partner→ABCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Prostaglandin secretion →	+1.768	+1.800	<.001	<.001	3	20
SKIN	Oligopeptide transport →	+0.112	+0.788	.001	.002	2	17
OVARY	Guanine nucleotide transport →	+0.121	+1.782	<.001	<.001	3	15
URINARY_TRACT	Tripeptide transmembrane transport →	+0.227	+2.132	<.001	<.001	3	15
LIVER	Oligopeptide transmembrane transport →	+0.159	+0.984	<.001	.001	2	16
OVARY	Nucleotide transmembrane transport →	+0.070	+1.485	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

Prostaglandin secretion by ABCC4 expression — BLOOD_Myeloma

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