ABCC11

Across TCGA pan-cancer cohorts, ABCC11 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ABCC11 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher ABCC11 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ABCC11 expression acts as an unfavorable survival marker.

MESO, ACC, and UCEC are the cancer types where ABCC11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	III,IV	0.052	0.567	<.001	36	view →
ACC	OS	Median	All	0.188	0.820	<.001	12	view →
UCEC	OS	Median	IV	0.259	0.770	<.001	12	view →
COAD	DFS	Median	III,IV	0.047	0.656	<.001	12	view →
LGG	DFS	Median	All	0.440	0.828	.026	3	view →
ESCA	OS	Median	II,III,IV	0.311	0.705	.037	3	view →
LUAD	OS	Median	II,III,IV	0.474	0.755	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ABCC11–MESO (OS)

Open the MESO breakdown →