ABCB6

Across TCGA patient cohorts, ABCB6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,559 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCB6-associated genes across cancer lineages are TRIM16L, ABTB1, and GMFG. Each is linked with ABCB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCB6-to-partner and partner-to-ABCB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB6 versus TRIM16L in LSCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB6→partner) and Y-score (partner→ABCB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM16L →	+1.714	+0.718	<.001	<.001	3	4
OV	ABTB1 →	-0.684	-0.415	<.001	<.001	3	3
UCEC	GMFG →	-1.138	-0.464	<.001	.001	3	3
UCEC	DOCK2 →	-0.838	-0.441	.002	.003	3	3
OV	CALHM2 →	-0.795	-0.442	<.001	<.001	3	3
GBM	RASGRP3 →	-0.447	-0.227	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,559 associations by consensus.

ABCB6 vs TRIM16L — LSCC

Explore this scatter interactively →