ABCB6

Across TCGA cell cohorts, ABCB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,041 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ABCB6-associated GO terms across cancer lineages are Cellular detoxification of cadmium ion, Heme transport, and Cellular detoxification of metal ion. Each is linked with ABCB6 in more than 15 cancer types. Because this analysis shows association rather than direction, both ABCB6-to-partner and partner-to-ABCB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular detoxification of cadmium ion grouped by ABCB6-low versus ABCB6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB6→partner) and Y-score (partner→ABCB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cellular detoxification of cadmium ion →	+1.001	+2.081	.002	<.001	2	16
LUNG_NSCLC_LUSC	Heme transport →	+0.172	+1.552	<.001	.003	3	14
URINARY_TRACT	Cellular detoxification of metal ion →	+1.192	+2.268	<.001	<.001	3	13
KIDNEY	Catecholamine transport →	+1.245	+1.534	.001	<.001	3	9
BLOOD_Myeloma	Melanosome assembly →	+0.144	+1.871	<.001	.001	3	8
SKIN	Calcium-independent cell-matrix adhesion →	+0.109	+1.098	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,041 associations by consensus.

Cellular detoxification of cadmium ion by ABCB6 expression — URINARY_TRACT

Explore this box plot interactively →