ABCB6

Across TCGA cell cohorts, ABCB6 mutation is significantly associated with the RNA expression of many other genes, with 315 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCB6-associated genes across cancer lineages are OR2J1, TULP2, and C20orf85. Each is linked with ABCB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCB6-to-partner and partner-to-ABCB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J1 grouped by ABCB6-low versus ABCB6-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB6→partner) and Y-score (partner→ABCB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR2J1 →	+0.006	+5.614	<.001	.002	3	2
SOFT_TISSUE	TULP2 →	+0.129	+3.906	<.001	.002	3	1
SOFT_TISSUE	C20orf85 →	+0.071	+4.369	<.001	<.001	3	1
SOFT_TISSUE	GPR32 →	+0.037	+3.295	<.001	.006	3	1
SOFT_TISSUE	OR4D6 →	+0.023	+3.977	<.001	.007	3	1
SOFT_TISSUE	ODF3 →	+0.017	+4.237	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 315 associations by consensus.

OR2J1 by ABCB6 expression — PANCREAS

Explore this box plot interactively →