ABCB5

Across TCGA patient cohorts, ABCB5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,444 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ABCB5-associated genes across cancer lineages are ALPK3, PPCDC, and CYP2J2. Each is linked with ABCB5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCB5-to-partner and partner-to-ABCB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB5 versus ALPK3 in LSCC, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB5→partner) and Y-score (partner→ABCB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ALPK3 →	+2.868	+1.981	.005	.004	3	3
LSCC	PPCDC →	+0.866	+1.720	.004	<.001	3	2
UCEC	CYP2J2 →	+1.001	+1.162	.007	.004	3	2
UCEC	ZNF300 →	+0.858	+0.915	.003	.001	3	2
BRCA	PDE4DIP →	+1.366	+1.446	.001	.004	3	2
UCEC	LINC01031 →	-0.591	-1.129	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,444 associations by consensus.

ABCB5 vs ALPK3 — LSCC

Explore this scatter interactively →