ABCB5

Across TCGA cell cohorts, ABCB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,257 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ABCB5-associated GO terms across cancer lineages are Lysosomal transport, Negative regulation of response to endoplasmic reticulum stress, and Regulation of proteasomal ubiquitin-dependent protein catabolic process. Each is linked with ABCB5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCB5-to-partner and partner-to-ABCB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal transport grouped by ABCB5-low versus ABCB5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB5→partner) and Y-score (partner→ABCB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Lysosomal transport →	+0.060	+0.485	.005	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of response to endoplasmic reticulum stress →	+0.088	+0.067	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.063	+0.045	<.001	.001	3	5
BONE	Positive regulation of autophagy →	+0.030	+0.262	.008	.007	3	5
BONE	Negative regulation of ferroptosis →	+0.089	+0.352	<.001	.005	3	5
BONE	Positive regulation of TOR signaling →	+0.059	+0.270	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,257 associations by consensus.

Lysosomal transport by ABCB5 expression — BONE

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