ABCB10P4

Across TCGA patient cohorts, ABCB10P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,484 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ABCB10P4-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Negative regulation of proteolysis involved in protein catabolic process, and Microtubule organizing center organization. Each is linked with ABCB10P4 in more than 16 cancer types. Because this analysis shows association rather than direction, both ABCB10P4-to-partner and partner-to-ABCB10P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA 3'-end processing grouped by ABCB10P4-low versus ABCB10P4-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB10P4→partner) and Y-score (partner→ABCB10P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of mRNA 3'-end processing →	+0.047	+0.064	<.001	<.001	3	15
UVM	Negative regulation of proteolysis involved in protein catabolic process →	+0.043	+0.017	<.001	.001	2	16
LAML	Microtubule organizing center organization →	+0.043	+0.099	<.001	<.001	3	15
THYM	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.041	+0.011	.001	<.001	1	17
LAML	Regulation of centriole replication →	+0.046	+0.076	.001	<.001	3	14
STAD	Regulation of microtubule cytoskeleton organization →	+0.035	+0.027	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,484 associations by consensus.

Positive regulation of mRNA 3'-end processing by ABCB10P4 expression — LAML

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