ABCB10

Across TCGA pan-cancer cohorts, ABCB10 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ABCB10 data layer compared with 29 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ABCB10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ABCB10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, READ, and UCEC are the cancer types where ABCB10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.573	0.924	<.001	35	view →
READ	DFS	Median	II,III,IV	0.082	0.800	<.001	21	view →
UCEC	DFS	Median	All	1.000	0.634	.024	16	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	DFS	Median	III,IV	0.046	0.648	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ABCB10–BRCA (OS)

Open the BRCA breakdown →