ABCB10

Across TCGA pan-cancer cohorts, ABCB10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABCB10 data layer compared with 29 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ABCB10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ABCB10 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, GBM, and LUAD are the cancer types where ABCB10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.908	0.706	.009	4	view →
GBM	OS	Tertile	All	0.864	0.629	.025	2	view →
LUAD	OS	Median	III,IV	0.718	0.276	.045	2	view →
CCRCC	DFS	Quartile	All	1.000	0.607	.009	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABCB10–HNSC (DFS)

Open the HNSC breakdown →