ABCB10

Across TCGA patient cohorts, ABCB10 mutation is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCB10-associated genes across cancer lineages are LINC02176, LINC01193, and TRBV7-9. Each is linked with ABCB10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCB10-to-partner and partner-to-ABCB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02176 grouped by ABCB10-low versus ABCB10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB10→partner) and Y-score (partner→ABCB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02176 →	+0.042	+2.766	.001	.006	3	3
BLCA	LINC01193 →	+0.486	+4.396	<.001	.002	3	3
UCEC	TRBV7-9 →	+0.875	+2.815	<.001	.001	3	2
UCEC	MRPS11 →	+0.360	+2.500	.005	.001	3	2
UCEC	EMID1 →	-1.173	-2.404	.003	.003	3	2
UCEC	PPP3R2 →	+0.039	+1.711	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

LINC02176 by ABCB10 expression — SKCM

Explore this box plot interactively →