ABCB10

Across TCGA cell cohorts, ABCB10 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCB10-associated genes across cancer lineages are OTOR, SSX7, and GALNTL5. Each is linked with ABCB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCB10-to-partner and partner-to-ABCB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OTOR grouped by ABCB10-low versus ABCB10-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB10→partner) and Y-score (partner→ABCB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OTOR →	+0.030	+5.087	<.001	.004	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
SKIN	GALNTL5 →	+0.039	+5.415	<.001	.004	3	1
SKIN	ODF1 →	+0.026	+6.022	<.001	.001	3	1
SKIN	GRIFIN →	+0.061	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CPO →	+0.163	+3.777	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OTOR by ABCB10 expression — URINARY_TRACT

Explore this box plot interactively →