ABCA8

Across TCGA patient cohorts, ABCA8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCA8-associated genes across cancer lineages are AOX1, ABCA9, and ABCA6. Each is linked with ABCA8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCA8-to-partner and partner-to-ABCA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA8 versus AOX1 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA8→partner) and Y-score (partner→ABCA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AOX1 →	+1.384	+0.684	.001	.004	3	7
OV	ABCA9 →	+1.138	+0.893	.001	<.001	3	7
GBM	ABCA6 →	+1.125	+0.710	<.001	<.001	3	7
BRCA	CHRDL1 →	+1.992	+0.611	.001	.006	3	6
HNSC	MEOX2 →	+1.197	+0.591	<.001	<.001	3	6
OV	ASPA →	+0.706	+0.774	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,609 associations by consensus.

ABCA8 vs AOX1 — OV

Explore this scatter interactively →