ABCA8

Across TCGA cell cohorts, ABCA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 866 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ABCA8-associated GO terms across cancer lineages are Aerobic electron transport chain, Proton motive force-driven mitochondrial ATP synthesis, and Retrograde transport, endosome to Golgi. Each is linked with ABCA8 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCA8-to-partner and partner-to-ABCA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by ABCA8-low versus ABCA8-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA8→partner) and Y-score (partner→ABCA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Aerobic electron transport chain →	+0.064	+0.344	<.001	.005	3	6
BLOOD_Lymphoma	Proton motive force-driven mitochondrial ATP synthesis →	+0.062	+0.344	<.001	.005	3	6
LUNG_NSCLC_LUAD	Retrograde transport, endosome to Golgi →	+0.036	+0.649	<.001	.001	3	6
CNS	Proton motive force-driven ATP synthesis →	+0.058	+0.957	.001	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.063	+0.164	<.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.069	+0.161	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 866 associations by consensus.

Aerobic electron transport chain by ABCA8 expression — BLOOD_Lymphoma

Explore this box plot interactively →