ABCA7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABCA7 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,885 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCA7-associated proteins across cancer lineages are DOCK11, IL16, and CORO1A. Each is linked with ABCA7 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA7-to-partner and partner-to-ABCA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA7 versus DOCK11 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA7→partner) and Y-score (partner→ABCA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDOCK11 →+0.542+0.759<.001.00134
GBMIL16 →+0.570+0.761<.001<.00134
CCRCCCORO1A →+0.548+0.530<.001<.00134
GBMINPP5D →+0.521+0.565<.001.00234
HNSCINPP5D_S243 →+0.569+0.695<.001<.00134
CCRCCLPXN →+0.479+0.565<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,885 associations by consensus.

ABCA7 vs DOCK11 — OV

Per-sample scatter of ABCA7 vs DOCK11 in OV (Pearson r = 0.38).

Explore this scatter interactively →

Exploration