ABCA6

Across TCGA pan-cancer cohorts, ABCA6 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ABCA6 data layer compared with 17 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ABCA6 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ABCA6 expression acts as an unfavorable survival marker.

LUAD, CCRCC, and LSCC are the cancer types where ABCA6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.599	1.000	.017	5	view →
CCRCC	DFS	Tertile	III,IV	0.293	0.801	.024	4	view →
LSCC	DFS	Quartile	II,III,IV	0.490	0.867	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ABCA6–LUAD (OS)

Open the LUAD breakdown →