ABCA6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABCA6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,327 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCA6-associated genes across cancer lineages are ADH1B, FAM110D, and LINC01352. Each is linked with ABCA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCA6-to-partner and partner-to-ABCA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA6 versus ADH1B in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA6→partner) and Y-score (partner→ABCA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAADH1B →+1.760+0.512.005.00335
HNSCFAM110D →+0.793+0.444.002<.00135
BRCALINC01352 →+0.788+0.491<.001.00835
BRCAABCA8 →+1.441+0.832.003.00135
BRCAJAM2 →+1.209+0.737<.001<.00135
BRCALHFPL6 →+1.479+0.682<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,327 associations by consensus.

ABCA6 vs ADH1B — BRCA

Per-sample scatter of ABCA6 vs ADH1B in BRCA (Pearson r = 0.62).

Explore this scatter interactively →

Exploration