ABCA6

Across TCGA cell cohorts, ABCA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,250 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ABCA6-associated GO terms across cancer lineages are Glycerolipid biosynthetic process, Androgen receptor signaling pathway, and Cellular response to iron ion. Each is linked with ABCA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCA6-to-partner and partner-to-ABCA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerolipid biosynthetic process grouped by ABCA6-low versus ABCA6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA6→partner) and Y-score (partner→ABCA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Glycerolipid biosynthetic process →	+0.055	+0.355	<.001	<.001	3	5
SKIN	Androgen receptor signaling pathway →	+0.103	+0.938	<.001	<.001	3	4
SOFT_TISSUE	Cellular response to iron ion →	-0.084	-0.397	.007	.003	3	4
BLOOD_Myeloma	Pyruvate transport →	-0.154	-0.207	.005	.002	2	5
BLOOD_Myeloma	Interleukin-1-mediated signaling pathway →	+0.077	+0.235	.006	.001	2	5
UPPER_AERODIGESTIVE_TRACT	Regulation of mesenchymal cell proliferation →	-0.094	-0.213	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,250 associations by consensus.

Glycerolipid biosynthetic process by ABCA6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →