ABCA6

Across TCGA cell cohorts, ABCA6 mutation is significantly associated with the RNA expression of many other genes, with 1,857 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCA6-associated genes across cancer lineages are SIRPD, TRIML1, and IAPP. Each is linked with ABCA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCA6-to-partner and partner-to-ABCA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIRPD grouped by ABCA6-low versus ABCA6-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA6→partner) and Y-score (partner→ABCA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SIRPD →	+0.011	+3.906	<.001	.009	3	2
BLOOD_Myeloma	TRIML1 →	+0.127	+3.906	.009	.009	3	2
LARGE_INTESTINE	IAPP →	+0.191	+1.617	.005	.003	3	2
SKIN	TNMD →	+0.075	+3.684	.002	.006	3	2
BLOOD_Leukemia	MMP20 →	+0.029	+2.536	.004	.009	3	2
BLOOD_Leukemia	ELF3 →	+1.021	+3.199	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,857 associations by consensus.

SIRPD by ABCA6 expression — BLOOD_Myeloma

Explore this box plot interactively →