ABCA3

Across TCGA patient cohorts, ABCA3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,516 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCA3-associated genes across cancer lineages are ZBTB16, SLC16A6, and C7. Each is linked with ABCA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA3-to-partner and partner-to-ABCA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA3 versus ZBTB16 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA3→partner) and Y-score (partner→ABCA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZBTB16 →	+1.426	+0.694	<.001	<.001	3	4
BRCA	SLC16A6 →	+1.071	+0.452	.002	.001	3	3
OV	C7 →	+2.163	+1.013	<.001	<.001	3	3
LUAD	ANLN →	-1.167	-0.416	<.001	.003	3	3
BRCA	EFCC1 →	+1.077	+0.399	<.001	<.001	3	3
LSCC	PPP4R4 →	+1.252	+0.529	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,516 associations by consensus.

ABCA3 vs ZBTB16 — LSCC

Explore this scatter interactively →