ABCA3

Across TCGA cell cohorts, ABCA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,983 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ABCA3-associated GO terms across cancer lineages are Negative regulation of cholesterol efflux, Intracellular sodium ion homeostasis, and Neurotransmitter secretion. Each is linked with ABCA3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ABCA3-to-partner and partner-to-ABCA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cholesterol efflux grouped by ABCA3-low versus ABCA3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA3→partner) and Y-score (partner→ABCA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of cholesterol efflux →	+0.263	+1.991	.002	.007	3	11
OVARY	Intracellular sodium ion homeostasis →	-0.188	-1.537	.001	<.001	3	10
LUNG_SCLC	Neurotransmitter secretion →	+0.076	+1.075	.004	.003	3	10
LUNG_NSCLC_LUAD	Acrosomal vesicle exocytosis →	+1.177	+1.558	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of matrix metallopeptidase secretion →	+0.242	+2.214	<.001	<.001	3	10
OVARY	Eosinophil homeostasis →	-1.143	-1.792	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,983 associations by consensus.

Negative regulation of cholesterol efflux by ABCA3 expression — STOMACH

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