ABCA2

Across TCGA patient cohorts, ABCA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,830 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCA2-associated proteins across cancer lineages are RPL5, RPL6, and LRSAM1. Each is linked with ABCA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA2-to-partner and partner-to-ABCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA2 versus RPL5 in BRCA, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA2→partner) and Y-score (partner→ABCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL5 →	-0.301	-1.210	<.001	<.001	3	4
GBM	RPL6 →	-0.409	-0.723	.003	<.001	3	4
BRCA	LRSAM1 →	+0.218	+0.721	<.001	<.001	3	4
UCEC	VTI1B →	-0.257	-0.723	.009	<.001	3	4
GBM	ASCC1 →	-0.179	-0.597	.004	.006	2	4
GBM	MAP3K4_T447 →	-0.614	-0.896	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,830 associations by consensus.

ABCA2 vs RPL5 — BRCA

Explore this scatter interactively →