ABCA2

Across TCGA patient cohorts, ABCA2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCA2-associated genes across cancer lineages are HAGLR, RASGRF1, and CDC6. Each is linked with ABCA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA2-to-partner and partner-to-ABCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA2 versus HAGLR in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA2→partner) and Y-score (partner→ABCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HAGLR →	+1.164	+0.428	.003	.001	2	4
GBM	RASGRF1 →	+1.329	+0.529	<.001	<.001	3	3
GBM	CDC6 →	-0.768	-0.517	.003	.002	3	3
LSCC	TRPV6 →	+0.546	+0.385	<.001	<.001	3	3
UCEC	MROH7 →	+0.596	+0.391	.005	<.001	3	2
OV	SHB →	+0.653	+0.467	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,628 associations by consensus.

ABCA2 vs HAGLR — UCEC

Explore this scatter interactively →