ABCA13

Across TCGA pan-cancer cohorts, ABCA13 Mutation is linked to patient survival in 15 of 34 cancer types, making it a survival-associated ABCA13 data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ABCA13 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ABCA13 expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, READ, and ACC are the cancer types where ABCA13 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.832	0.595	<.001	30	view →
READ	OS	Median	III,IV	0.511	0.913	<.001	29	view →
ACC	OS	Median	II,III,IV	0.161	0.608	.010	13	view →
LIHC	DFS	Median	II,III,IV	0.066	0.471	<.001	13	view →
BLCA	OS	Median	IV	0.195	0.491	.005	12	view →
COAD	OS	Median	IV	0.182	0.727	.001	9	view →
KIRP	OS	Median	III,IV	0.247	0.809	.003	6	view →
TGCT	DFS	Median	All	0.146	0.801	.020	6	view →
STAD	OS	Median	III,IV	0.859	0.418	.041	6	view →
PRAD	DFS	Median	All	0.717	0.937	.004	6	view →
ESCA	OS	Median	All	0.213	0.915	.005	6	view →
HNSC	OS	Median	III,IV	0.808	0.319	.039	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

ABCA13–UCEC (DFS)

Open the UCEC breakdown →